A case report on acrania with omphalocele

Congenital/fetal malformations are structural, functional, and/or biochemical molecular defects present at birth. Prevalence of congenital fetal anomalies in developing countries 2 to 3% newborns and about 94% severe birth defects. Acrania is a lethal malformation characterized by partial or complete absence flat bones cranial vault. Another anomaly, omphalocele, ventral defect the umbilical ring resulting herniation abdominal viscera, one most common wall seen newborn. Omphalocele associated with trisomy. Incidence acrania India 1.4 per 1000 births. omphalocele 1 4000 case 29-year-old, G2P1L1 14 weeks days gestation attended OPD ultrasonographic report showing omphalocele. The sonographic scan revealed fully developed brain having no calvarium. was covered thin membranous structure. Facial structures frog eye appearance, open spina bifida. Normal well-coordinated movements were noted body parts. abdomen showed central mass protruding out from anterior wall. membrane contains small intestines. There direct insertion cord into midline Patient counselled regarding condition its outcome. willing for termination. Medical termination pregnancy done. A single dead female fetus placental weighing 250 gm.